The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.
| ISBN: | 9783319460901 |
| Publication date: | 14th November 2016 |
| Author: | Daniele Focosi |
| Publisher: | Springer an imprint of Springer International Publishing |
| Format: | Hardback |
| Pagination: | 188 pages |
| Series: | Resistance to Targeted Anti-Cancer Therapeutics |
| Genres: |
Oncology |