Huntington's disease (HD) is a progressive, fatal, dominant inherited neurodegenerative disorder caused by an unstable expansion of CAG repeats within the coding region of the IT15 gene that encodes for a protein called huntingtin (htt). The clinical hallmark of HD is a severe motor impairment, but cognitive and psychiatric symptoms are early clinical features in HD that often appear before the onset of motor signs. This book discusses the prevalence, pathogenesis and treatment of HD.
| ISBN: | 9781536108279 |
| Publication date: | 1st February 2017 |
| Author: | Christina Hughes |
| Publisher: | Nova Science Publishers an imprint of Nova Science Publishers, Inc |
| Format: | Hardback |
| Pagination: | 170 pages |
| Series: | Neurology--Laboratory and Clinical Research Developments |
| Genres: |
Neurology and clinical neurophysiology |