Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery. With extensively updated content and 21 new chapters, this text examines: quality and efficiency of drug target validation and potential drug compound selection reducing assay costs and improvement in assay technology data quality improvement trends in drug discovery how drug screening can minimize adverse drug effects recent advancements, including: high content screening; protein-protein interactions; high-throughput crystallization; lead optimization; chemoinformatics and microfluidics technologies; target validation by genomics, proteomics, and siRNA; structure-based drug design; automation; and medicinal chemistry
ISBN: | 9781420061680 |
Publication date: | 24th June 2009 |
Author: | Ramakrishna BristolMeyers Squibb Company, Princeton, New Jersey, USA Seethala |
Publisher: | CRC Press Inc an imprint of Taylor & Francis Inc |
Format: | Hardback |
Pagination: | 504 pages |
Series: | Drugs and the Pharmaceutical Sciences |
Genres: |
Biology, life sciences Pharmaceutical chemistry and technology Medical research |