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A comprehensive history of cancer - one of the greatest enemies of medical progress - and an insight into its effects and potential cures, by a leading expert on the illness.In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years.The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out 'war against cancer'. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary.From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge.Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.
Siddhartha Mukherjee (Author), Stephen Hoye (Narrator)
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Brain Bugs: How the Brain's Flaws Shape Our Lives
A lively, surprising tour of our mental glitches and how they arise. With its trillions of connections, the human brain is more beautiful and complex than anything we could ever build, but it's far from perfect: our memory is unreliable; we can't multiply large sums in our heads; advertising manipulates our judgment; we tend to distrust people who are different from us; supernatural beliefs and superstitions are hard to shake; we prefer instant gratification to long-term gain; and what we presume to be rational decisions are often anything but. Drawing on striking examples and fascinating studies, neuroscientist Dean Buonomano illuminates the causes and consequences of these "bugs" in terms of the brain's innermost workings and their evolutionary purposes. He then goes one step further, examining how our brains function-and malfunction-in the digital, predator-free, information-saturated, special-effects-addled world that we have built for ourselves. Along the way, Brain Bugs gives us the tools to hone our cognitive strengths while recognizing our inherent weaknesses. "Intriguing take on behavioral economics, marketing, and human foibles."-Kirkus Reviews
Dean Buonomano (Author), William Hughes (Narrator)
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More than half a century ago, the naturalist Farley Mowat accepted an assignment to investigate why wolves were killing Arctic caribou. Mowat's account of the summer he lived in the frozen tundra alone - studying the wolf population and developing a deep affection for these wild creatures (who were no threat to caribou or man) - is today celebrated as a classic of nature writing, at once a tale of remarkable adventure and an indelible record of the myths and magic of wolves. Never Cry Wolf was made into a major motion picture by Walt Disney Productions.
Farley Mowat (Author), Adam Sims (Narrator)
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Brain Bugs: How the Brain’s Flaws Shape Our Lives
A lively, surprising tour of our mental glitches and how they arise With its trillions of connections, the human brain is more beautiful and complex than anything we could ever build, but it's far from perfect: our memory is unreliable; we can't multiply large sums in our heads; advertising manipulates our judgment; we tend to distrust people who are different from us; supernatural beliefs and superstitions are hard to shake; we prefer instant gratification to long-term gain; and what we presume to be rational decisions are often anything but. Drawing on striking examples and fascinating studies, neuroscientist Dean Buonomano illuminates the causes and consequences of these "bugs" in terms of the brain's innermost workings and their evolutionary purposes. He then goes one step further, examining how our brains function-and malfunction-in the digital, predator-free, information-saturated, special-effects-addled world that we have built for ourselves. Along the way, Brain Bugs gives us the tools to hone our cognitive strengths while recognizing our inherent weaknesses.
Dean Buonomano (Author), William Hughes (Narrator)
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In the Realm of Hungry Ghosts: Close Encounters With Addiction
Profoundly original, bestselling writer and physician Gabor Maté looks at the epidemic of addictions in our society, tells us why we are so prone to them and what is needed to liberate ourselves from their hold on our emotions and behaviors. Gabor Maté is a staff physician at the Portland Hotel, a residence and harm reduction facility in Vancouver's Downtown Eastside. His patients are challenged by life-threatening drug addictions, mental illness, Hepatitis C or HIV and, in many cases, all four. But if Dr. Maté`s patients are at the far end of the spectrum, there are many among us who are also struggling with addictions. Drugs, alcohol, tobacco, work, food, sex, gambling and excessive inappropriate spending: what is amiss with our lives that we seek such self destructive ways to comfort ourselves? And why is it so difficult to stop these habits, even as they threaten our health, jeopardize our relationships and corrode our lives? Starting with a close view of his drug addicted patients, Dr. Maté looks at his own history of compulsive behavior, weaving a story of real people who struggle with addiction with the latest research on addiction and the brain. A bold synthesis of clinical experience, insight and cutting edge scientific findings, Dr. Maté sheds light on this most puzzling of human frailties. He proposes a compassionate approach to helping drug addicts and, for the many behavior addicts among us, to addressing the void addiction is meant to fill.
Gabor Maté (Author), Daniel Brooklyn Maté (Narrator)
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Moonwalking with Einstein: The Art and Science of Remembering Everything
The blockbuster phenomenon that charts an amazing journey of the mind while revolutionizing our concept of memory An instant bestseller that is poised to become a classic, Moonwalking with Einstein recounts Joshua Foer's yearlong quest to improve his memory under the tutelage of top 'mental athletes.' He draws on cutting-edge research, a surprising cultural history of remembering, and venerable tricks of the mentalist's trade to transform our understanding of human memory. From the United States Memory Championship to deep within the author's own mind, this is an electrifying work of journalism that reminds us that, in every way that matters, we are the sum of our memories. From the Trade Paperback edition.
Joshua Foer (Author), Mike Chamberlain (Narrator)
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Ladies and gentlemen of the jury, everyone is familiar with the tired cliches: women are bad drivers and are not good with money; only guys play video games and they give bad directions. Dan Abrams tackles the toughest case of his career in Man Down. Drawing on years of legal experience and research studies, Abrams explains step-by-step why women are better than men in just about every way imaginable, from managing money to flying planes to living longer. Abrams uses his trademark charm to get his point across without opining on the issue himself. Chock-full of fun facts and conversation starters, this book may not end the debate of men versus women, but it will definitely make it more interesting.
Dan Abrams (Author), Dan Abrams (Narrator)
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A pioneering neuroscientist shows how the long-sought merger of brains with machines is about to become a paradigm-shifting reality. Imagine living in a world where people use their computers, drive their cars, and communicate with one another simply by thinking. In this stunning and inspiring work, Duke University neuroscientist Miguel Nicolelis shares his revolutionary insights into how the brain creates thought and the human sense of self-and how this might be augmented by machines, so that the entire universe will be within our reach. Beyond Boundaries draws on Nicolelis's ground-breaking research with monkeys that he taught to control the movements of a robot located halfway around the globe by using brain signals alone. Nicolelis's work with primates has uncovered a new method for capturing brain function-by recording rich neuronal symphonies rather than the activity of single neurons. His lab is now paving the way for a new treatment for Parkinson's, silk-thin exoskeletons to grant mobility to the paralyzed, and breathtaking leaps in space exploration, global communication, manufacturing, and more. Beyond Boundaries promises to reshape our concept of the technological future, to a world filled with promise and hope. *** Please contact member services for additional documents.
Miguel Nicolelis (Author), Patrick Egan (Narrator)
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Who are you? It's the most fundamental of human questions. Are you the type of person who tilts at windmills, or the one who prefers to view them from the comfort of an air-conditioned motorcoach? Our personalities are endlessly fascinating-not just to ourselves but also to our spouses, our parents, our children, our co-workers, our neighbors. As a highly social species, humans have to navigate among an astonishing variety of personalities. But how did all these different permutations come about? And what purpose do they serve? With her trademark wit and sly humor, Hannah Holmes takes readers into the amazing world of personality and modern brain science. Using the Five Factor Model, which slices temperaments into the major factors (Extraversion, Neuroticism, Agreeableness, Conscientiousness, and Openness) and minor facets (such as impulsive, artistic, or cautious), Holmes demonstrates how our genes and brains dictate which factors and facets each of us displays. Are you a Nervous Nelly? Your amygdala is probably calling the shots. Hyperactive Hal? It's all about the dopamine. Each facet took root deep in the evolution of life on Earth, with Nature allowing enough personal variation to see a species through good times and bad. Just as there are introverted and extroverted people, there are introverted and extroverted mice, and even starfish. In fact, the personality genes we share with mice make them invaluable models for the study of disorders like depression, schizophrenia, and anxiety. Thus it is deep and ancient biases that guide your dealings with a very modern world. Your personality helps to determine the political party you support, the car you drive, the way you eat M&Ms, and the likelihood that you'll cheat on your spouse. Drawing on data from top research laboratories, the lives of her eccentric friends, the conflicts that plague her own household, and even the habits of her two pet mice, Hannah Holmes summarizes the factors that shape you. And what she proves is that it does take all kinds. Even the most irksome and trying personality you've ever encountered contributes to the diversity of our species. And diversity is the key to our survival.
Hannah Holmes (Author), Susan Denaker (Narrator)
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Paradigm Shift: Consciousness, Meditation and Quantum Physics: A Conversation with Samuel Avery
In this engaging conversation, Samuel Avery explores the compelling ideas in his new audiobook The Buddha and the Quantum. He takes us on a brief journey through the 100 year history of quantum physics and the 3,000 year history of Buddhist meditation to show us that the discoveries of the Buddha and physicist Max Planck were one and the same.
Samuel Avery (Author), Samuel Avery (Narrator)
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Genome: The Autobiography of a Species In 23 Chapters
The genome's been mapped. But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.
Matt Ridley (Author), Simon Prebble (Narrator)
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The Red Queen: Sex and the Evolution of Human Nature
Referring to Lewis Carroll's Red Queen from Through the Looking-Glass, a character who has to keep running to stay in the same place, Matt Ridley demonstrates why sex is humanity's best strategy for outwitting its constantly mutating internal predators. The Red Queen answers dozens of other riddles of human nature and culture -- including why men propose marriage, the method behind our maddening notions of beauty, and the disquieting fact that a woman is more likely to conceive a child by an adulterous lover than by her husband. Brilliantly written, The Red Queen offers an extraordinary new way of interpreting the human condition and how it has evolved.
Matt Ridley (Author), Simon Prebble (Narrator)
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