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The Song of the Cell: An Exploration of Medicine and the New Human
From Pulitzer Prize-winning and #1 New York Times bestselling author of The Emperor of All Maladies and The Gene, The Song of The Cell is the third book in this extraordinary writer's exploration of what it means to be human-rich with Siddhartha Mukherjee's revelatory and exhilarating stories of scientists, doctors, and all the patients whose lives may be saved by their work.In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves-hearts, blood, brains-are built from these compartments. Hooke christens them 'cells'.The discovery of cells-and the reframing of the human body as a cellular ecosystem-announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer's, dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID-all could be viewed as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies.In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces readers with writing so vivid, lucid, and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjee's own experience as a researcher, doctor, and prolific reader, The Song of the Cell is both panoramic and intimate-a masterpiece.
Siddhartha Mukherjee (Author), Abhishek Sharma (Narrator)
Audiobook
The Song of the Cell: An Exploration of Medicine and the New Human
Brought to you by Penguin. From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, about the fundamental unit of life. Rich with Mukherjee's revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer's exploration of what it means to be human. In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek look down their hand-made microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It is the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves - hearts, blood, brains - are built from these compartments. Hooke christens them 'cells'. The discovery of cells -and the reframing of the human body as a cellular ecosystem - announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer's dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia - all could be re-conceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. In The Song of the Cell, Mukherjee tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. He seduces readers with writing so vivid, lucid and suspenseful that complex science becomes thrilling. Told in six parts, laced with Mukherjee's own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate - a masterpiece. © Siddhartha Mukherjee 2022 (P) Penguin Audio 2022
Siddhartha Mukherjee (Author), Dennis Boutsikaris (Narrator)
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A Cancer in the Family: Take Control of Your Genetic Inheritance
Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it's estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family's story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows listeners how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers listeners to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.
Siddhartha Mukherjee, Theodora Ross (Author), Marguerite Gavin, Siddhartha Mukherjee (Narrator)
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*Shortlisted for the Baillie Gifford Prize for Non-Fiction 2016* The Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a 'unit of heredity'. It intersects with Darwin's theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds - from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes. This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history - the story of Mukherjee's own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to "read" and "write" the human genome - unleashing the potential to change the fates and identities of our children. Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity - and a vision of both humanity's past and future.
Siddhartha Mukherjee (Author), Dennis Boutsikaris (Narrator)
Audiobook
From the Pulitzer Prize-winning, bestselling author of The Emperor of All Maladies-a magnificent history of the gene and a response to the defining question of the future: What becomes of being human when we learn to "read" and "write" our own genetic information?The extraordinary Siddhartha Mukherjee has a written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. Throughout the narrative, the story of Mukherjee's own family-with its tragic and bewildering history of mental illness-cuts like a bright, red line, reminding us of the many questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In superb prose and with an instinct for the dramatic scene, he describes the centuries of research and experimentation-from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Thomas Morgan to Crick, Watson and Rosa Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. As The New Yorker said of The Emperor of All Maladies, "It's hard to think of many books for a general audience that have rendered any area of modern science and technology with such intelligence, accessibility, and compassion...An extraordinary achievement." Riveting, revelatory, and magisterial history of a scientific idea coming to life, and an essential preparation for the moral complexity introduced by our ability to create or "write" the human genome, The Gene is a must-read for everyone concerned about the definition and future of humanity. This is the most crucial science of our time, intimately explained by a master.
Siddhartha Mukherjee (Author), Dennis Boutsikaris (Narrator)
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The Emperor of All Maladies: A Biography of Cancer
A magnificent, beautifully written "biography" of cancer"from its first documented appearances thousands of years ago through the epic battles to cure, control, and conquer it, to a radical new understanding of its essence. The Emperor of All Maladies reveals the many faces of an iconic, shape-shifting disease that is the defining plague of our generation. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, arrogance, paternalism, and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all out "war against cancer." Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary. The book reads like a literary thriller with cancer as the central character. From the Persian Queen Atossa whose Greek slave may have cut off her diseased breast to the nineteenth-century recipients of primitive radiation and chemotherapy, to Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimens in order to survive"and to increase the store of human knowledge.
Siddhartha Mukherjee (Author), Fred Sanders (Narrator)
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Essential, required listening for doctors and patients alike: A Pulitzer Prize-winning author and one of the world's premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine-and how understanding these principles can empower us all.Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a "science"? Sciences must have laws-statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question-a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline-culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee's signature eloquence and passionate prose, The Laws of Medicine is a critical book, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.
Siddhartha Mukherjee (Author), Santino Fontana (Narrator)
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A comprehensive history of cancer - one of the greatest enemies of medical progress - and an insight into its effects and potential cures, by a leading expert on the illness.In The Emperor of All Maladies, Siddhartha Mukherjee, doctor, researcher and award-winning science writer, examines cancer with a cellular biologist's precision, a historian's perspective, and a biographer's passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years.The story of cancer is a story of human ingenuity, resilience and perseverance, but also of hubris, arrogance and misperception, all leveraged against a disease that, just three decades ago, was thought to be easily vanquished in an all-out 'war against cancer'. Mukherjee recounts centuries of discoveries, setbacks, victories and deaths, told through the eyes of predecessors and peers, training their wits against an infinitely resourceful adversary.From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteeth-century recipient of primitive radiation and chemotherapy and Mukherjee's own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through toxic, bruising, and draining regimes to survive and to increase the store of human knowledge.Riveting and magesterial, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments and a brilliant new perspective on the way doctors, scientists, philosophers and lay people have observed and understood the human body for millennia.
Siddhartha Mukherjee (Author), Stephen Hoye (Narrator)
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